Cresilon's FDA-cleared TRAUMAGEL uses plant-based polymer technology to control severe bleeding in seconds — no pressure, no prep, now available to EMS, military, and trauma hospitals nationwide.
Photo source:
Cresilon
Every year, 1.75 million people die from uncontrolled bleeding — not from their injuries, but from
blood that couldn't be stopped in time (WHO, 2024). Hemorrhage causes over 80%
of operating-room deaths following major trauma, and on the battlefield, 91% of
potentially survivable combat deaths trace back to the same cause (Kauvar et
al., Journal of Trauma, 2006; Eastridge et al., Journal of Trauma and Acute
Care Surgery, 2012).
Cresilon, a Brooklyn-based biotechnology company, built a direct answer
to that problem. Their plant-based hemostatic gel, TRAUMAGEL, received
FDA 510(k) clearance in August 2024, launched nationwide in January 2025, and
in 2026 earned Cresilon the #1 spot in Fast Company's Most Innovative Medical
Device Companies — #46 across every industry on earth.
TRAUMAGEL is a flowable hemostatic gel made from plant-derived
polysaccharide polymers — the same structural molecules found in plant cell
walls. It comes in a sterile, single-use 30mL prefilled syringe, requires zero
preparation, and is designed for immediate use at the point of injury.
When applied to a wound, the gel flows into the injury — filling
irregular spaces, adapting to complex wound geometries — and forms an instant
mechanical barrier that supports the body's natural clotting process. No heat.
No electricity. No manual pressure needed. Bleeding slows, then stops, in
seconds.
Unlike gauze or tourniquets that rely on compression, TRAUMAGEL works
through contact chemistry. The plant-derived polymers interact directly with
blood, creating a physical seal that conforms to the wound's shape — whether
it's a clean laceration, a deep puncture, a gunshot wound, or a partial
amputation.
Three properties define it in the field:
FAST — no mixing, no activation, no warming. Open the syringe and apply.
EASY — usable by EMTs, paramedics, military medics, police officers, and
firefighters without specialized surgical training.
RELIABLE — effective from point of injury through hospital transport and into the
emergency room. A wound stabilized with TRAUMAGEL stays stabilized.
TRAUMAGEL is commercially available now across the United States. It is
cleared for use by EMTs, paramedics, first responders, emergency departments,
trauma hospitals, military units, and law enforcement agencies. It is not a
consumer product — procurement is through professional medical suppliers
including Life-Assist and Pacific Biomedical, which ships nationwide within 24
hours.
In March 2026, Cresilon received an Innovative Technology contract from
Vizient — the largest provider-driven healthcare performance improvement
company in the US, representing over $156 billion in annual purchasing volume —
further opening access across academic medical centers, community hospitals,
and integrated health networks nationwide.
TRAUMAGEL isn't theoretical. In 2026, Cresilon presented two
peer-reviewed case studies at the Special Operations Medical Association (SOMA)
Scientific Assembly — one covering prehospital hemorrhage control in the field,
another documenting a partial hand amputation with ulnar artery transection
successfully treated before hospital arrival. A 2026 PubMed-indexed study
followed TRAUMAGEL use across traumatic extremity injuries including tourniquet
removal cases. A 2025 large animal randomized controlled trial confirmed high
efficacy in severe hemorrhage scenarios.
Before entering human medicine, Cresilon spent five years validating the
same technology in veterinary medicine through VETIGEL — which has now
supported over 65,000 procedures worldwide. That clinical foundation built the
evidence base that earned FDA clearance for human use.
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