BrainSense technology records real brain activity during deep brain stimulation to support more personalized neurological therapy.
Photo source:
bioworld
Deep brain stimulation, or DBS, is a therapy
used to treat conditions such as Parkinson’s disease, essential tremor, and
dystonia. It works by sending electrical pulses to specific areas of the brain
to help manage symptoms.
Traditionally, DBS settings are adjusted during
clinic visits based on patient feedback and short observations. However, brain
activity changes throughout the day. Medication cycles, movement, stress, and
sleep all affect how the brain behaves. Without continuous data, it can be
difficult to fine-tune therapy for these changes.
BrainSense was developed to address this
limitation by providing access to real brain signals during daily life, not
just during appointments.
BrainSense
is a sensing feature built into certain deep-brain stimulation systems. It
allows the implanted leads to record small electrical signals from the brain
while stimulation is being delivered.
These signals, known as local field potentials,
reflect patterns of neural activity linked to symptoms and movement. By
collecting this information, BrainSense provides objective data that can be
used alongside patient-reported experiences.
The same electrodes used to deliver stimulation
also collect brain signals. This means no additional implants are required. The
system records activity continuously or at specific times, depending on its configuration.
Clinicians can review this data using
programming tools. They can compare brain activity with symptom changes,
medication timing, or daily routines. This helps inform decisions about stimulation settings.
BrainSense enables a form of therapy called
adaptive deep-brain stimulation. In this mode, stimulation can change
automatically in response to detected brain signals.
When certain patterns linked to symptoms
increase, stimulation can rise. When those patterns decrease, stimulation can
be reduced. This approach aims to provide more consistent symptom control
throughout the day without constant manual adjustment.
With BrainSense, clinicians can identify which
electrode contacts produce the most useful brain signals. This helps during
initial setup and later adjustments.
Instead of relying only on short clinical
assessments, therapy decisions can be supported by data collected during
real-world activity. Over time, this can lead to more personalized and
responsive care plans.
BrainSense is not a standalone therapy. It
enhances existing deep-brain stimulation systems by adding a layer of brain
signal monitoring.
It is used in approved DBS treatments for neurological conditions, according to regional guidelines and indications. Its
role is to support ongoing therapy optimization as symptoms and brain activity
evolve.
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